Title and Copyright:
Nasal Antigen Response, ©2005.

Media:
Adobe Illustrator.

Collaborator:
Robert Kern, MD. Department of Otolaryngology– Head and Neck Surgery, Northwestern University; Chicago, Illinois.

Description:
Antigen stimulation in Waldeyer's Ring leads to presentation of the antigen to CD4+ T Cells with resulting B Cell activation and plasma cell production of dimeric IgA. This Ig A is then secreted by the nasal mucosa to protect against further antigenic stimulation.

Presented as:
Kern RC (presenter), Seiberling KA, Conley DB, Haines K, Tripathi A, Walsh WE, Schleimer RP, Grammer LC. Fungi, staphylococci and the etiology of chronic rhinosinusitis. American Rhinologic Society, Combined Spring Otolaryngology Meetings; Boca Raton, FL: May 14, 2005.